Scientist I

Job Title: Scientist I

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. ​

We are looking for an enthusiastic PhD-level scientist interested in developing and implementing in vitro cellular models within the Global Investigative Toxicology group at Sanofi USA for safety applications. The incumbent will perform in vitro studies to assess the role of therapeutic modalities and uncover mechanisms that lead to unexpected toxicity of small and large molecule candidates by employing fit-for-purpose cutting edge in vitro models. The successful candidate must have good collaborative skills to smoothly work with Sanofi colleagues across sites and with external vendors, a high level of scientific rigor in their work, and exemplary communication skills. You will collaborate with a diverse group of experts at Sanofi to push the boundaries of science and help to bring innovative and safe medications to the patients.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities

• Develop and optimize physiologically relevant in vitro models, including providing technical expertise, design and execute qualification plans, and establish relevant endpoint assays to dissect the molecular mechanisms of toxicity.

• Independently review literature to generate hypotheses for experimental testing.  Design and execute relevant experiments to test hypotheses, including data analysis and its interpretation.

• Collaborate with external vendors on technology and assay evaluation, where appropriate.

• Work with project teams to address and investigate safety mechanisms and help projects meet development timelines.

• Author investigative reports to support inclusion of results in regulatory submissions as needed.

• Represent Sanofi on external consortia.

About You

Requirements & Qualifications

• PhD in a biological field with 0-3 years of postdoctoral experience OR Master’s Degree with 4+ years relevant experience in an academic or biopharmaceutical setting.

• A degree in toxicology, pharmacology, immunology, biomedical engineering, or equivalent is preferred.

• Proven experience and expertise in mammalian cell culture (primary, iPSC), imaging (high content, confocal), molecular biology (RNA, DNA, protein) endpoints, and biochemical endpoints is a must.

• Working knowledge of organ-on-a-chip/MPS, 3D models, or complex in vitro systems will be an advantage.

• Experience in toxicity assays related to liver, kidney or immunology is also a plus.

• Established record of scientific contribution in peer-reviewed journals and scientific symposiums.

• Excellent verbal and written communication skills.   

Terms of employment

• Occasional domestic travel to scientific conferences as permitted by Sanofi travel policies. Availability to start in Q1 2026.

Location information

• The position is lab-based and requires the incumbent to be on-site most days of the week in Cambridge, MA.

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

• Be part of an active, innovative scientific group

• Gain broad expertise in novel in vitro models

• Have diverse opportunities to collaborate global

• Be highly recognized for success

• Receive excellent benefits and compensation

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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