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Job Title: Scientist, Advanced Ocular In Vitro Models

Location: Cambridge, MA

About the Job

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

Sanofi is seeking a motivated scientist to drive advanced ocular in vitro models to support the Ophthalmology research pipeline. As a Scientist in the Advanced Ocular In Vitro Models group you will establish physiologically relevant models for Ophthalmology diseases, including retinal diseases, macular degeneration, glaucoma, and other vision-related indications. The successful candidate will work closely with cross-functional teams and stakeholders to implement advanced in vitro models in the discovery, validation, and development of novel ophthalmic therapeutics. This position offers the exciting opportunity to make significant contributions to the future of ophthalmology therapeutics and bring transformative vision-preserving treatments to patients around the world.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

About Sanofi:
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main Responsibilities

• Design, develop and validate advanced in vitro ocular models for early and late-stage ophthalmic research.

• Establish differentiation protocols for induced pluripotent stem cell (IPSC) derived cell types relevant to ocular disease.

• Integrate automation and robotics to scale cell culture and differentiation workflows.

• Evaluate and implement innovative advanced ocular in vitro models (co-cultures, organoids, MPS, organ-on-chip, bioprinting).

• Apply in vitro models to study ocular disease mechanisms, validate therapeutic targets, assess multi-modality therapeutics, and evaluate safety.

• Collaborate across interdisciplinary teams in a highly matrixed research environment.

• Deliver high-quality scientific presentations and documentation to support project milestones.

• Communicate findings effectively through internal presentations and external publications.

• Provide scientific mentorship and technical guidance to junior team members.

About You

• Earned Bachelor’s degree in a life sciences, bioengineering or related field with 6+ years OR Master’s degree in a life sciences, bioengineering or related field with 3+ years of relevant experience, preferably in biotech or pharmaceutical settings.

• Experience in iPSC-based 2D/3D differentiation for disease modeling and drug discovery required, with a preference in ocular cell types (RPE, RGCs, Microglia, and/or Endothelial).

• Hands-on experience with robotics, automated cell culture systems, and/or protocol scaling.

• Experienced with using iPSC-derived cells for high-throughput pharmacological and genetic screening.

• Expertise in qPCR, -omics technologies, immunocytochemistry, and advanced imaging technologies and analysis.

• Proven record of research contributions and scientific publications.

• Experience with computational and statistical analysis tools (e.g., R, Python) preferred.

• Background in bioengineering with a focus on cellular systems, microfluidics, and translational research preferred.

• Experienced in scaling 2D/3D differentiation protocols using automated platforms preferred.

• Experienced in high-throughput assay development using iPSC-derived cells highly preferred. 

• Ability to work independently and collaboratively in cross-functional teams.

• Ability to multi-task and adapt to rapidly changing priorities and deadlines.

• Strong critical thinking, analytical, and problem-solving skills.

• Exceptional written and verbal communication skills, with proven expertise in effectively presenting scientific data in a matrixed environment.

• Strong interpersonal skills, with the ability to build excellent working relationships.

• Exceptional organizational and time-management skills, lab notebook practices, and attention to detail.

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Pursue Progress. Discovery Extraordinary.

Werde Teil von Sanofi und starte mit uns in eine neue Ära der Wissenschaft – wo dein persönliches Wachstum genauso wegweisend ist wie unsere Arbeit. Wir investieren in dich, damit du weiterkommst, schneller denkst und Dinge möglich machst, die vorher undenkbar waren. Du wirst Grenzen verschieben, Gewohntes hinterfragen und smarte Lösungen entwickeln, die direkt bei den Menschen ankommen, für die wir da sind. Bereit, die Wunder der Wissenschaft zu jagen und Leben zu verbessern? Dann lass uns gemeinsam Großes bewegen – und das Außergewöhnliche entdecken.

Bei Sanofi stehen allen die gleichen Chancen offen – unabhängig von Herkunft, Hautfarbe, Religion, Geschlecht, Nationalität, sexueller Orientierung, Alter, Staatsangehörigkeit, Familienstand, Behinderung, Geschlechtsidentität, Veteranenstatus oder anderen gesetzlich geschützten Merkmalen.