
Manufacturing and Supply
Where the
miracles of
science are made
a reality for patients
Upstream Manager Scientist - Vaccine
At a glance
Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.
Job Title: Upstream Manager Scientist - Vaccine
Location: Swiftwater, PA
About the Job
Primaryresponsibilitywillbetoworkasapartoftheworkingvirusbank(WVB)generationgroup.WVBis a recombinant baculovirus seed for manufacturing drug substances for Influenza & COVID vaccines.
We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.
Main Responsibilities:
Maintenance of insect cells in suspension culture at different scales (shake flasks, waves, small and pilot size bioreactors)
Transfection of insect cells, baculovirus plaque purification, infection & scale-up of baculovirus stocks
Sampling cell culture and preparation of samples for analytical testing
Performing standard molecular biology tasks such as baculovirus DNA purification, PCR, restriction endonucleases digest, DNA agarose gel electrophoresis
Performing analysis of recombinant protein expression by Western blot, SDS-PAGE, and single radial immunodiffusion techniques (SRID)
Responsible for completing paperwork for each task
Maintenance of the labs and ordering of supplies
Communicate with co-workers and present data on a regular basis at the group and department meetings
Flexible in time management
Complies with all company policies and standard
How:
Behavesaccordingtocompanyvaluesand competencies.
Influencesinternally;forwardthinkingwithanattitudeofcollaboration,optimization, efficiency, continuous improvement.
Proactivelyanticipatesandeffectivelycommunicatessuccesses,constraints,conflicts, solutions and actions for resolution.
Proactivelyresolvesconflicts,removesroadblockstoexecutionwithinsphereofinfluence; escalates to functional management when appropriate. \
Fostersrelationshipswithpartners,expertsfromotherfunctionsandcustomersinorderto achieve technical objectives.
*Key Responsibilities may differ among employees with the same job title and may change over time, in accordance with business needs.
About You
BASIC QUALIFICATIONS:
BachelororMasterinbiology,cellbiology,molecularbiology,biochemistry,chemistryor related field.
Experienceinmicrobialandmolecularbiologytechniquesand,procedures,andaseptic techniques.
AbilitytoutilizeMicrosoftExcel,PowerPointandWordtoperformtasks
Abilitytoplanandconductlaboratoryexperiments,evaluate,andinterpretdata.
Abilitytoworkwithminimumsupervision.
Detail-orientedandabilitytoprioritizeassignments.
FluentinbothwrittenandspokenEnglish
PREFERRED QUALIFICATIONS:
1yearofExperienceinmicrobialandmolecularbiologytechniquesand,procedures,and aseptic techniques.
Experienceincellcultureproceduresandassociatedaseptictechniques
Experienceinmolecularbiologyprocedures
Willingtoworkchangingschedulesandhoursasneeded
Abletoworkeffectivelyinacollaborativeteam
Detail-orientedandabletoprioritizeassignments
Strongverbalandwrittencommunicationskills.
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

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Why work with us
- We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.
- Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.
- Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.
- We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.
All-in on diversity
At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

"Manufacturing and Supply is the bridge between the science that happens in research laboratories and the people and communities we serve."

Brendan O’Callaghan
Executive Vice President of Manufacturing and Supply
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