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Manufacturing and Supply

Manufacturing and Supply
Where the
miracles of
science
are made
a reality
for patients

Integrated Manufacturing Systems Engineer

Swiftwater, Pennsylvania Salary Range   USD 84,750.00 - 122,416.66
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At a glance

Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.

Job Title: Integrated Manufacturing Systems Engineer

Location: Swiftwater, PA

About the Job

We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families. 

Sanofi is an innovative global healthcare company with one purpose: to pursue scientific miracles to improve lives. Our team strives to transform the practice of medicine, connecting our science to communities in meaningful ways. Within our Sanofi Manufacturing & Supply Ambition, we’re redefining our strategy, culture, and processes to make a tangible impact worldwide. In this role, you'll join the Automation & Manufacturing Systems department at our Swiftwater site, supporting directly the Manufacturing Execution System (MES) in the Integrated Manufacturing Systems (IMS) team.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?​

Main Responsibilities:

  • The IMS Engineer will be responsible to configure, maintain, and update MES to support production needs effectively.

  • Support system implementation and upgrades.

  • Configure and optimize MES, Data Historian, and Kepware systems.

  • Manage and maintain technical data, including equipment properties.

  • Troubleshoot and continuously improve IMS performance.

  • Lead MES-related projects for new products and production setups in APU.

  • Collaborate with cross-functional teams, including IT, Automation, and Manufacturing Excellence, in defining and implementing strategy to demonstrate the improvement changes are fit for intended use throughout entire life cycle, and to ensure that changes are qualified and maintained accordingly.

  • Provide support during regulatory inspections and site audits as quality oversight and SME of IMS.

    Partner and collaborate closely with cross functional teams to achieve site’s GMP/operational readiness goals/objectives and ensuring all project deliverables are met on time.


About You


Education and experience:

  • Bachelor’s or Master’s degree in Science, Engineering, or related Life Sciences or Technology fields.

  • A minimum 4-7 years of relevant experience, preferably in Manufacturing Execution System, (Siemens MES Opcenter Execution Pharma Product) in the pharmaceutical or biotechnology industry.

Key technical competencies and soft skills:

  • Strong knowledge of MES, Data Historian, and Kepware systems.

  • Experience with data management and equipment property configuration.

  • Project management skills, especially in MES implementations.

  • Understanding of interface management between MES and manufacturing equipment.

  • Ability to troubleshoot and enhance system performance.

  • Familiarity with regulatory and industry standards for IMS.

  • Driven team player with the ability to collaborate and work with cross-functional teams (including global partners) to meet project timelines.

  • Good communication skills to present strategies to the site management and other functions.



Related KPIs and metrics

Success rate in implementing local BSO initiatives.

Interface uptime and reliability between MES and equipment.

Configuration accuracy for MES, Data Historian, and Kepware systems.

Data integrity and accuracy in technical data management.

Reduction in system downtime through proactive troubleshooting.

Why Choose Us?

  • Bring the miracles of science to life alongside a supportive, future-focused team.

  • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. 

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Pursue Progress. Discover Extraordinary.

Progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. You can be one of those people. Chasing change, embracing new ideas and exploring all the opportunities we have to offer. Let’s pursue progress. And let’s discover extraordinary together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.

Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com

Apply now
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Why work with us

  • We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.

  • Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.

  • Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.

  • We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.

All-in on diversity

At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

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"Manufacturing and Supply is the bridge between the science that happens in research laboratories and the people and communities we serve."

Brendan O’Callaghan

Executive Vice President of Manufacturing and Supply

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Explore how Sanofi is transforming pharmaceutical manufacturing and supply chains with cutting-edge technology, digital innovation, and sustainable practices. Discover career opportunities where you can help deliver life-changing medicines efficiently and responsibly.

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