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Manufacturing and Supply

Manufacturing and Supply
Where the
miracles of
science
are made
a reality
for patients

Senior Manager (Upstream), MSAT

Singapore, Singapore
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At a glance

Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.

Manufacturing Sciences, Analytics and Technology (MSAT) drives the industrialization and continuous improvement of biological processes and products. The function adopts new technologies and digital innovations while serving as the custodian of manufacturing process knowledge.

Positioned at the intersection of R&D and manufacturing, MSAT is a multidisciplinary function providing expertise in process sciences, manufacturing, process modelling, statistical analysis, validation, and technology transfer.

The Senior Manager, Upstream MSAT (Modulus Singapore) holds decision-making authority across key areas including talent management, team development, and budget allocation. From a technical perspective, the role is accountable for upstream process platforms and material-related decisions across process transfer, validation, manufacturing support, and investigations.

This role also drives innovation through the implementation of new technologies and materials, while ensuring process robustness, optimization, and continuous platform improvement.

Key Responsibilities

1. Team Leadership & Development

  • Build, lead, and develop a high-performing team of MSAT upstream scientists and engineers.

  • Define team structure, workflows, and deliverables to support process transfer and manufacturing operations.

  • Coach and develop team members, fostering a culture of accountability, continuous improvement, and open communication.

  • Drive employee engagement and enhance the organization’s attractiveness for talent in Singapore’s manufacturing sciences landscape.

2. Process Transfer & Project Leadership

  • Develop upstream process and engineering strategies to ensure consistency across products and platforms.

  • Establish systems and tools for standardization and knowledge management.

  • Lead site- or team-level programs/projects, including:

    • Defining manufacturing processes

    • Establishing validation and control strategies

    • Authoring complex technical documents and regulatory inputs

  • Ensure delivery of projects on time, within budget, and to quality standards.

3. Manufacturing Support

  • Organize MSAT upstream support to meet manufacturing needs, including after-hours on-call support.

  • Provide scientific expertise for routine operations and troubleshooting.

  • Lead complex investigations, assessments, and CAPA activities.

  • Ensure upstream process robustness for assigned products.

  • Drive Continued Process Verification (CPV) activities.

4. Lifecycle Management & Innovation

  • Act as the primary site contact for assigned products, ensuring alignment with global technical teams.

  • Lead initiatives for process and program improvements, including yield optimization and new technology implementation.

  • Serve as a subject matter expert and potentially a network-level key opinion leader.

Requirements

Core Competencies

  • Strong leadership with strategic vision and operational mindset.

  • Effective communicator in cross-functional and multicultural environments.

  • Excellent analytical and problem-solving capabilities with a data-driven approach.

  • Self-directed with the ability to work autonomously and drive initiatives.

  • Scientifically curious with a continuous improvement mindset.

Technical & Educational Background

  • Degree (or higher) in Biotechnology, Biological Sciences, Chemical Engineering, or related field.

  • Extensive industry experience in mammalian biopharmaceutical processes, including:

    • Process engineering

    • Technology transfer

    • Process validation

    • Manufacturing support

  • Strong understanding of upstream processes and parameter interactions.

  • Hands-on experience in pilot-scale or large-scale manufacturing environments (cell culture and/or purification).

  • Solid knowledge of cGMP requirements and current regulatory expectations.

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Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com

Final compensation will be determined based on factors such as experience, skills, expertise, location, and others. Employees may be eligible to participate in company employee benefit programs.

Apply now
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Why work with us

  • We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.

  • Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.

  • Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.

  • We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.

All-in on diversity

At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

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"Manufacturing and Supply is the bridge between the science that happens in research laboratories and the people and communities we serve."

Brendan O’Callaghan

Executive Vice President of Manufacturing and Supply

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