R&D
Where your curiosity drives the
miracles of
science
Operational Excellence Leader, R&D
At a glance
Bring your curiosity to a team where deep immunoscience meets cutting-edge innovation. Across oncology, rare diseases, neurology, and vaccines, you’ll work at the intersection of lab science and AI-powered discovery — all while collaborating across boundaries to turn breakthrough ideas into real-world impact. Whether you want to deepen your scientific expertise or grow as a leader, you’ll find the opportunity here.
Job Title: Operational Excellence Leader
Location: Morristown, NJ
About the Job
Sanofi R&D is undergoing a significant transformation to accelerate innovation, increase productivity, and deliver breakthrough medicines to patients faster. To enable this ambition, Sanofi is establishing R&D Transformation, a new organization strategic modernization team within R&D Operations, designed to drive enterprise-level changes through disciplined execution, operational excellence, and sustainable value realization.
R&D Transformation acts as a catalyst for change across the R&D organization, bridging strategic priorities with operational execution to ensure rapid adoption and lasting impact. Led by the Global Head of R&D Transformation, the organization is structured around three core pillars:
Execution of strategic modernization initiatives: Translating R&D strategic priorities endorsed by the R&D Leadership Team into actionable, end-to-end execution plans, ensuring speed, coherence, and seamless integration into business as usual.
Operational excellence: Designing, simplifying, and continuously improving high-impact R&D processes to maximize productivity, reduce complexity, and enable organizational agility.
Post-merger integration: Leading R&D-wide integration efforts to unlock scientific, cultural, and organizational value from M&A transactions.
The R&D Operational Excellence Leader is a key member of the R&D Operations Transformation team, serving as a trusted advisor to optimize end-to-end functionality across the value chain. This role focuses on partnering with R&D stakeholders to identify, design, and deliver high-impact performance solutions that drive organizational effectiveness and productivity. Success in this role means enabling R&D Functions to achieve process excellence through strategic advisory support and expert guidance on priority initiatives.
As an R&D Operational Excellence Leader, you will serve as a strategic partner and change catalysts, advising R&D functions on performance improvement opportunities and guiding the selection and execution of optimal deployment approaches (i.e., booster, digital, end-to-end). You will design tailored solutions, manage multiple client engagements simultaneously, and deliver measurable, sustainable results that match stakeholder expectations.
Join the engine of Sanofi’s mission where deep immunosenescent meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.
About Sanofi
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Main Responsibilities
Solution Design & Delivery:
Facilitate cross-functional workshops with R&D Functions and stakeholders to map, streamline, and standardize processes, ensuring alignment with strategic priorities
Develop comprehensive project plans, deliverables, and success metrics for each consulting engagement
Design and implement change management strategies that ensure stakeholder buy-in and sustainable adoption
Provide expert guidance on digital/IA solution selection, deployment, and optimization to maximize value realization
Stakeholder Engagement & Communication:
Communicate effectively across all organizational levels, translating complex concepts into actionable insights for diverse audiences
Facilitate alignment of improvement initiatives with R&D strategic priorities through structured stakeholder engagement
Present findings, recommendations, and Progress updates to senior leadership and steering committees
Navigate matrix organizations to influence decision-making and drive consensus among diverse stakeholder groups
Performance Monitoring & Value Realization:
Develop and track key performance indicators (KPIs) to measure operational efficiency and demonstrate consulting impact
Monitor engagement progress, proactively identify and remove roadblocks, and challenge teams to achieve breakthrough results
Conduct post-implementation reviews to validate value delivery and identify continuous improvement opportunities
Document lessons learned and best practices to enhance consulting methodologies and organizational knowledge
Knowledge Transfer & Capability Building:
Coach and mentor R&D staff on lean methodologies, process improvement techniques, and change management best practices
Design and deliver training programs that build internal capability and reinforce sustainable change
Develop and continuously optimize standards, playbooks, and toolkits based on engagement insights and client feedback
Foster a culture of continuous improvement through knowledge sharing and capability development
About You
Basic Qualifications
You will gain exposure to enterprise-level transformation topics and contribute directly to shaping the execution and realization of Sanofi R&D's strategic priorities. You will operate with independence, executive maturity, and strong analytical rigor, balancing objective challenges with collaborative partnership to drive sustainable change.
Experience:
Experience: 10+ years in operational excellence consulting, internal consulting, or advisory roles, preferably within pharmaceutical or biotechnology R&D environment
Stakeholder Management: Proven track record of managing multiple stakeholder engagements simultaneously and delivering measurable results
Project Delivery: Demonstrated success leading end-to-end projects from diagnostic through implementation and value realization
Change Leadership: Strong exposure to change management methodologies, stakeholder engagement strategies, and digital transformation initiatives
Industry Expertise: Deep understanding of pharmaceutical R&D operations, regulatory environments, and industry best practices
Soft Skills:
Consulting Mindset: Client-focused approach with strong business acumen and ability to balance strategic thinking with pragmatic execution
Stakeholder Management: Exceptional ability to build trusted advisor relationships, influence without authority in matrix organizations, and navigate complex political landscapes
Adaptability & Agility: High degree of flexibility to work across multiple projects, adjust to changing priorities, and thrive in ambiguous environments
Leadership & Influence: Capacity to drive initiatives and decision-making, shape vision, challenge status quo with innovation and pragmatism, and inspire trust
Coaching & Development: Strong mentoring abilities with capacity to develop people, provide structured feedback, and build organizational capability
Autonomy & Initiative: Self-directed with ability to take calculated risks, anticipate potential issues, and drive results with minimal supervision
Technical Skills:
Methodology Expertise: Deep knowledge of Lean, Six Sigma, and other process improvement methodologies (FIT4Future); ability to select and adapt approaches based on client context
Functional Knowledge: Excellent understanding of R&D processes, value chains, and operational dynamics
Analytical Capabilities: Superior analytical and problem-solving skills with ability to synthesize complex data into actionable insights
Financial Acumen: Solid financial analysis and management accounting knowledge to quantify business cases and demonstrate ROI
Solution Design: Proven ability to design tailored solutions that address root causes and deliver sustainable impact
Education:
Bachelor's degree is required. Master's degree in a scientific field, engineering, business administration, or related discipline; MBA or advanced degree a plus
Languages:
English (fluent)
Desired Skills:
Familiarity with R&D processes and regulatory requirements in the pharmaceutical industry
Proficiency in data analysis and visualization tools (e.g., Power BI, advanced Excel)
Certification in Lean Six Sigma (Green Belt or Black Belt)
Experience with digital transformation and AI/automation solution deployment
Why Choose Us
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
Help improve the lives of millions of people globally by making drug development quicker and more effective.
Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
Pursue Progress. Discover Extraordinary.
Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.
Final compensation will be determined based on demonstrated experience, skills, location, and other relevant factors. Employees may be eligible to participate in Company employee benefit programs.
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Why work with us
- Expand your horizons. Grow through curiosity, with support to move, learn, and lead in a culture that champions mentorship, mobility, and bold development.
- Accelerate results with technology. Harness the power of AI and automation to push scientific boundaries and reimagine what's possible in drug discovery.
- Impact through inclusive innovation. Help deliver better science and fairer outcomes by driving inclusive research that reaches more people, in more meaningful ways.
- Turn patient needs into breakthrough science. Drive scientific breakthroughs that start with patient needs – and end in treatments that change lives.
Meet Nils Libert, Associate Scientist
Meet Nils Libert, an Associate Scientist in Belgium, where he plays a key role in advancing groundbreaking research. Learn how his work helps drive innovation, uncover new scientific possibilities, and contribute to life-changing treatments that impact patients around the world.
"At Sanofi, we are building an R&D engine powered by the best science, digital innovation, and a commitment to transforming the lives of patients around the world."
Houman Ashrafian
EVP & Head of R&D
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