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Vaccines

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mRNA System Engineer

Marcy-l'Étoile, France
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Who we are

Every day, 2.5 million Sanofi vaccine doses reach patients worldwide - powered by bold ideas, cutting-edge science, and passionate people like you. Across every stage — from discovery to delivery — Sanofians are shaping the future of vaccines. In global R&D hubs, exceptional offices, and state-of-the-art manufacturing sites, we’re reimagining what’s possible. But science alone isn’t enough — it’s the extraordinary minds behind it that truly make the difference.

Le contenu du poste est libellé en anglais car il nécessite de nombreuses interactions avec nos filiales à l’international, l'anglais étant la langue de travail.

This job offer is accessible to all, regardless of gender.


Job title:mRNA System Engineer

  • Location: Marcy l'Etoile (France)
  • Grade: Level 2
  • Hiring Manager: Fabien Pertuy

About the job

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

About the job:

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. Join our mRNA Center of Excellence as Senior Engineer, mRNA Systems Engineering and you'll contribute to building innovative systems that industrialize AI within our vaccine development platform, while enjoying opportunities to work at the cutting edge of digital and biotechnologies.

We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.

As a Senior Engineer within mRNA Systems Engineering, your work will be instrumental to transform research models into products that directly impact vaccine development. To this end you will interact with AI/ML scientists tackling hot topics in every area of our end-to-end mRNA platform, including process modeling, sequence design, formulation optimization, translational models and more.

Main responsibilities:

  • Design, build and maintain key systems for AI industrialization within the mRNA Center of Excellence
  • Collaborate as a member of a multidisciplinary development team to create innovative solutions
  • Interact directly with users to gather feedback and implement improvements in an AGILE mindset
  • Ensure best practices in software development are consistently applied across projects
  • Contribute to educating collaborators on software development best practices and system thinking
  • Develop backend systems and solutions that support the mRNA platform's objectives
  • Help drive the technical vision for systems that reduce friction in the software world

About you

Experience:

  • Practical experience developing backend systems and pipelines (e.g. Kubernetes, Metaflow, ArgoWorkflows), frontend experience is a plus
  • Experience with DevOps, GitOps and MLOps practices and tools (e.g. Github Actions, ArgoCD, Weights and Biases)
  • Practical experience developing backend systems and pipelines (e.g. Kubernetes, Metaflow, ArgoWorkflows). Customer Experience (CX) skills and experience designing and building frontend is a plus

Soft and technical skills:

  • Proficient in Python programming with strong software engineering skills and culture (e.g. code quality and sustainability, documentation, testing)
  • System thinking approach with experience in designing software architectures
  • Strong collaboration skills for working in multidisciplinary environments
  • Customer orientation and experience working in an AGILE way

Education:

  • Master's or Engineering degree in Computer Sciences or equivalent, and significant industry experience. An appetite for LifeScience/Biomedical Research is important to align your purpose with Sanofi’s, actual experience in the field is a plus

Languages:

  • Fluency in English required, French language skills are a plus


Why choose us?

  • Bring the miracles of science to life alongside a supportive, future-focused team
  • Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally
  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact
  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave
  • Work in a truly multidisciplinary environment at the interface of digital technologies and biotechnologies
  • Contribute to an innovative drug design platform based on mRNA technology that is currently advancing vaccine candidates to clinical trials
  • Be part of a customer and product-oriented team focused on reducing friction in the software world so that scientists can focus on the bigger picture

"This role offers a unique opportunity to apply advanced software engineering skills to help shape the future of vaccine development. You'll be working at the intersection of AI and mRNA technology, directly contributing to systems that could ultimately help protect millions of people worldwide."
Fabien Pertuy, Head of mRNA Systems Engineering

PursueProgress. Discover Extraordinary

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.  

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Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com

Apply now
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Why work with us

  • We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.

  • Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.

  • Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.

  • We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.

What does it take to protect the world from disease?

For over a century, we’ve been pioneering breakthroughs that help protect millions from diseases like polio, influenza, RSV, and more. And we’re not stopping there.

Powered by groundbreaking technologies - mRNA platforms, recombinant proteins, and AI-driven insights - we’re pushing the boundaries of science.

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"I’m immensely proud of the pace of our innovation – the urgency by which our teams are working to transform the practice of medicine."

Thomas Triomphe

Executive Vice President, Vaccines

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Sanofi’s mRNA Center of Excellence

Step into the future of healthcare with Sanofi’s mRNA Center of Excellence. Discover how a global team is transforming medicine with cutting-edge mRNA technology – and explore the skills, inspirations, and breakthroughs driving this revolution. Ready to shape the future?

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About Sanofi Vaccines

Explore our commitment to protecting global health through the power of vaccines. We’re building healthier communities with innovative solutions that save millions of lives each year. Dive into the future of vaccines, discover the diseases we’re tackling, and learn why vaccination is critical at every stage of life.

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