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MES Reliability Engineer

Hyderabad, India Permanent Posted on   Jul. 24, 2025 Closing on   Aug. 02, 2025
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About the Job

  • Job Summary

  • The MES Reliability Engineer ensures the stability and performance of Manufacturing Execution Systems (MES) to maximize operational value. This role serves as a bridge between development and operations teams, taking a proactive approach to prevent downtime, optimize system performance, and ensure the reliable operation of manufacturing systems that are critical to production.

Main Responsibilities

  • Incident Management and Resolution

  • Anticipate, Prevent and Lead incident response efforts to swiftly resolve MES service disruptions, minimizing impact on manufacturing operations

  • Conduct thorough analyses of system failures and implement preventive measures to avoid future incidents

  • Develop/ maintain/ follow standard operating procedures for incident response in manufacturing environments

  • System Reliability and Availability

  • Develop and implement strategies to ensure high availability and reliability of MES platforms/ applications/ systems

  • Monitor system health, analyze performance metrics, and proactively identify and resolve potential issues before they impact production

  • Establish and maintain system reliability standards and best practices specific to manufacturing environments

  • Continuous Improvement

  • Innovate and iterate on processes and tools to improve operational efficiency and system resilience

  • Implement and optimize monitoring solutions to provide real-time visibility into MES performance and health

  • Security and Compliance

  • Ensure all MES systems and processes adhere to industry best practices, GMP requirements, and regulatory security standards

  • Implement and maintain security measures to safeguard manufacturing data and systems against unauthorized access and cyber threats

  • Collaboration and Stakeholder Management

  • Work closely with Manufacturing, IT, Quality, and other stakeholders to align technical solutions with operational goals

  • Serve as a subject matter expert in MES reliability engineering, providing guidance and support to teams across the organization

  • Collaborate with vendors and technology partners to resolve complex system issues and implement improvements

  • Learning and Development

  • Stay current with the latest trends and technologies in reliability engineering, manufacturing systems, and software development practices

  • Foster a culture of learning and continuous improvement within the manufacturing technology team

  • Cross-Functional Coordination and Global Support

  • Coordinate with Technology & Infrastructure teams to ensure seamless integration and operation of MES systems

  • Collaborate with partners to address infrastructure gaps and optimize system performance

  • Manage incidents including assignment, reporting, problem management, and P-task follow-ups

  • Conduct thorough impact assessments for system changes and incidents

  • Lead and coordinate application/infrastructure task forces across manufacturing sites worldwide

  • Establish clear communication channels between technical teams and manufacturing operations globally

  • Expected Outcomes

  • Achieve and maintain MES system uptime and reliability targets defined by organizational objectives and Service Level Agreements (SLAs)

  • Reduce the frequency and duration of MES-related incidents and downtime that impact manufacturing operations

  • Streamline deployment processes for MES updates and enhancements, ensuring minimal disruption to production

  • Enhance system security and ensure compliance with all relevant regulations and standards

About You

  • Experience

  • 8+ years of experience in reliability engineering in Manufacturing context

  • Demonstrated experience in pharmaceutical manufacturing and GxP regulated environments

  • 5+years Hands-on experience with MES platforms, specifically Siemens OPCenter EXPH or Werum PAS-X

  • Experience working in global, multi-site manufacturing organizations

  • Education

  • Bachelor's degree in computer science, Engineering, Information Technology, or related technical field

  • Technical Skills

  • Strong knowledge of MES architecture, interfaces, and integration 

  • Proficiency in ITIL standards and Service Management processes including Incident Management, Problem Management, Change Management, and Release Management

  • Advanced troubleshooting skills with ability to identify root causes and implement effective solutions

  • Knowledge of installation and upgrade procedures for MES systems

  • SNOW and monitoring systems

  • Experience with digital technologies including AWS or Azure cloud environments, containers, microservices, and DevOps practices

  • Working knowledge of infrastructure technologies and services including:

  • Network administration

  • Windows system administration

  • Database management (Oracle and PostgreSQL)

  • Mendix low-code development platform

  • Scripting capabilities for automation and system management

  • Industry Knowledge

  • Understanding of GMP requirements, regulatory compliance in pharmaceutical manufacturing and computer system validation, data integrity principles

  • Familiarity with pharmaceutical manufacturing processes and workflows,

  • Soft Skills

  • Strong customer/user orientation with focus on service excellence

  • Excellent problem-solving skills and ability to work under pressure during system incidents

  • Strong communication skills with ability to explain technical concepts to non-technical stakeholders

  • Coordination with worldwide teams (vendor, partners…)

  • Demonstrated leadership in cross-functional team environments

  • Ability to manage multiple priorities in a fast-paced environment

  • Self-motivated with ability to work independently and as part of a global team

  • Preferred Qualifications

  • ITIL certification

  • Experience with Industry 4.0 concepts and digital transformation in manufacturing

  • Good knowledge of containerization technologies and microservices architecture

  • Language:

  • Fluency in English, additional language is a plus

  • Working Environment:

  • Flexibility to contribute occasionally on operations out of working hours

  • Global, matrix organization environment

  • Must be able to work effectively across different time zones and cultures

Pursue Progress, discover Extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.

Watch our ALL IN videoand check out our Diversity Equity and Inclusion actions at sanofi.com!

Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

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