
Manufacturing and Supply
Where the
miracles of
science are made
a reality for patients
Project Management Office Lead (all genders)
At a glance
Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.
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Background
Sanofi has decided to invest into a new large state-of-the art facility for Insulin Drug Substance in Frankfurt, Germany. We’re enhancing our legacy of excellence and build on decades of expertise on the whole value chain of insulin manufacturing. The new facility will be designed as a fully automated, green, modern, and state-of-the-art biologics facility considering specific process requirements of all insulins. A large global and highly cross-functional program organization will be established to lead and execute the program until commercial routine manufacturing.
About the Role
The PMO Lead for the Insulin Flex Facility (IFF) ensures structured project execution, governance adherence, and stakeholder alignment within this major Sanofi investment program. This role drives the implementation of global guidelines, standards, and gating processes while establishing robust governance structures. The position focuses on comprehensive program management including budgeting, milestone tracking, risk management, reporting, and strategic communication to enable successful project delivery.
The successful candidate will coordinate project management efforts, facilitating collaboration across international teams and ensuring consistent methodologies are applied. The role also entails transversal interactions with multiple stakeholders requiring excellent communication skills and stakeholder management expertise. The PMO Lead will work closely with the global functions, the insulin cluster, the China cluster, as well as with the E2E lead.
Main Responsibilities
1. Program Orchestration & Standards Implementation
- Prepare and conduct Steering Committees for this Billion-euro program
- Establish governance structures, supporting tools, and KPIs for program success
- Ensure adherence to global guidelines, gating processes, and standards
- Monitor environmental changes and support project teams in problem-solving
- Manage and optimize the program budget for cost-effective delivery
2. Data Excellence & Digital Innovation
- Develop URS for project management tools and generate stakeholder-specific reports
- Track milestones, budgets, and deliverables using enterprise project management software
- Maintain single source of truth for program data and implement AI use cases
- Develop dashboards and Progress tracking mechanisms with KPIs
- Leverage advanced technologies for data visualization and predictive analytics
3. Stakeholder Engagement & Cultural Leadership
- Drive structured communication and change strategy across the program
- Manage diverse stakeholder needs and foster positive team atmosphere
- Coordinate cross-functional collaboration and ensure effective information flow
- Proactively identify and address potential roadblocks
- Build strong relationships with global functions, insulin cluster, and China cluster
About You
Education: Advanced degree in engineering, pharmacy, biotechnology or related field; Project Management certification from PMI, IPMA or equivalent is highly desirable
Experience: 6 years in a pharmaceutical industry experience; proven expertise in project management and program governance, demonstrated team leadership skills
Technical Expertise: Experience in program management within the pharmaceutical industry with skills in budgeting, risk management and KPI tracking. Ability to manage high-stakes projects and engage cross-functional teams. Strong ability to develop executive reports, dashboards, and structured documentation. Proficiency in PMO tools (e.g., SharePoint, dashboards, risk matrices); Familiarity with pharmaceutical manufacturing processes and regulatory requirements
Languages: Excellent communication skills both in English and German, additional languages a a plus; Intercultural experience (EU/US/Asia esp. China) is a plus

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Why work with us
- We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.
- Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.
- Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.
- We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.
All-in on diversity
At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

"Manufacturing and Supply is the bridge between the science that happens in research laboratories and the people and communities we serve."

Brendan O’Callaghan
Executive Vice President of Manufacturing and Supply
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