
Manufacturing and Supply
Where the
miracles of
science are made
a reality for patients
Head of Engineering & Maintenance M&S Campus Frankfurt – all genders
At a glance
Our teams produce and deliver over 4 billion units of medicines and vaccines every year, ensuring every breakthrough gets to the people who need it most.
Our state-of-the-art facilities, AI-powered smart factories, and cutting-edge automation are redefining what’s possible: ensuring treatments reach patients faster, safer, and more sustainably than ever before. This is where your skills, ambition, and passion can shape the future of healthcare.
About our team
We are Sanofi. We are an innovative global healthcare company, driven by one purpose: we chase the miracles of science to improve people’s lives.
Our teams across the world strive to transform the practice of medicine, turning the impossible into the possible for patients. We’re transforming strategy, culture, and process through one Sanofi Manufacturing & Supply Ambition that will connect our science to the communities we serve.
As the Head of Site Engineering & Maintenance, you will ensure the efficient operation, maintenance, and continuous improvement of all site facilities and production equipment, in accordance with regulatory requirements and Sanofi guidelines. You will provide Engineering leadership across the plant, ensuring optimal performance and reliability of production systems, and occasionally cover responsibilities related to site infrastructure and safety.
About the M&S Campus Frankfurt
The M&S Campus Frankfurt is a Campus which includes 4 different Manufacturing Units: API Production, Fill & Finish and Device Assembly as well as a Launch Unit to ensure first to market launch of new products. It comprises around 4.000 employees across more than 10 buildings. The site produces a full Insulin range, legacy Pharma products, Oncology and Biologics (packaging), and monoclonal antibodies (device assembly and packaging). Our technologies include API production via fermentation, sterile filling, device assembly, packaging, and special forms (e.g., powder coating, creams, ointments, implants, microparticles).
About the job
As Head of Campus Engineering & Maintenance for our M&S Campus Frankfurt, you will lead and provide leadership to the maintenance and engineering functions in accordance with regulatory and Group Engineering, HSE & Quality guidelines. You will be responsible for an Engineering & Maintenance department covering approximately 650 employees.
This position requires not only technical expertise but also profound transformation & change management skills to lead the recently started transformation journey of the site from an engineering & maintenance perspective.
Strategic Leadership
- Lead the transformation to a centralized and efficient Engineering and Maintenance department
- Own the site master plan and contribute to building the Investment Strategy and Long Range Plan
Operational Excellence
- Ensure efficient, reliable, and high-quality maintenance, facilities, and utilities operations
- Manage the functionality and proper maintenance of all equipment in compliance with GMP
- Deploy and ensure effectiveness of the Asset Management and Maintenance Roadmap
- Translate site goals into departmental goals and manage annual objectives, financial budgets, and headcount targets
- Establish and manage relationships with contractors to ensure quality and compliance
Compliance & Continuous Improvement
- Partner with Quality and HSE to drive harmonization and fulfillment of compliance programs
- Drive a culture of continuous improvement using Lean methodologies
- Participate in the Sanofi Global Engineering and Maintenance network for establishing common standards
Main responsibilities:
- Provide input and studies to support decision making process with site leadership team and central function
- Deciding on the initiation and funding of capital projects
- Capital Project delivery model (workforce, study, execution & CQV plan, contracts with 3rd party…) for design to closure
- Making decisions on the allocation of the reliability engineering to optimize manufacturing output and maintenance cost
- Making decisions on the allocation of the engineering and maintenance budget to various projects and operational needs
- Advising on strategies to ensure all engineering, automation & maintenance activities comply with industry regulations & standards
- Implementing process improvements to enhance efficiency, safety, and quality within the engineering and maintenance groups
- Selection and management of external contractors and suppliers to ensure they meet the company’s standards and requirements
- on site needs and strategic workforce planning
About you
Experience / Education / Languages:
- Biopharma Manufacturing: Extensive experience managing engineering and maintenance in a GMP-compliant biopharma environment.
- Technical Maintenance: Significant experience in maintaining and optimizing biopharma production equipment and facilities.
- Bachelor’s degree in engineering, preferably in Biochemical Engineering. A master's or Ph.D. in Engineering, Biotechnology, or a related field is highly desirable.
- Professional Certifications: Relevant certifications such as PMP (Project Management Professional) or Six Sigma can be advantageous.
- German, Fluency in English, both written and verbal
Soft skills:
- Enterprise Leader: is able to have the E2E vision of the business, prioritizing the common interest for the benefit of Sanofi and the patients. Can connect the dots for their team and keep them engaged with the vision.
- Transformation Leader: Acts as change management and culture role model to foster employee’s engagement and build a psychologically safe and collaborative workplace.
- Decision Maker: Takes timely and data-based decisions in a fast moving and complex environment to drive performance and Progress. Promotes an environment where decisions are taken at the right level.
- Performance Champion: Embraces digital innovation, AI, GenAI to democratize data and drives continuous improvement initiatives to enhance efficiency, quality, safety, and cost effectiveness.
- Business Ally: Understands the business landscape Industry & business/client groups knowledge to translate the challenges & bring added value. Stays current with global external trends and integrates insights into strategies achieving sustainable competitive advantage.
- People Developer: Unleashes the potential of each one and prepares the leaders of the future. Takes bold decisions to ensure the right talents are at the right place.
Technical skills:
- Project Management: Proficiency in planning, executing, and monitoring large-scale projects.
- Technical Expertise: In-depth knowledge of engineering & maintenance principles on pharmaceutical manufacturing processes.
- Regulatory Knowledge: Familiarity with pharmaceutical industry regulations, including GMP and FDA standards.
- Problem-Solving: Excellent analytical and problem-solving skills to address technical issues.
Pursue progress, discover Extraordinary.
Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.
At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.
Watch our ALL IN videoand check out our Diversity Equity and Inclusion actions at sanofi.com!
Pursue Progress. Discover Extraordinary.
Progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. You can be one of those people. Chasing change, embracing new ideas and exploring all the opportunities we have to offer. Let’s pursue progress. And let’s discover extraordinary together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity.
Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com

Find out more about this location

Why work with us
- We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.
- Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.
- Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.
- We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.
All-in on diversity
At Sanofi, diverse perspectives fuel the best solutions for patients. Hear from Monique Vessey, our Supply Chain Transformation Leader, on how her background shapes her approach to delivering life-changing medicines.

"Manufacturing and Supply is the bridge between the science that happens in research laboratories and the people and communities we serve."

Brendan O’Callaghan
Executive Vice President of Manufacturing and Supply
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