Manufacturing and Supply
Where the
miracles of
science are made
a reality for patients

Job Title: Operational Excellence Performance Lead

• Location: Cambridge, MA

About the Job

The Operational Excellence Performance Lead is a key member of the EM&S Operational Excellence team, responsible for fostering the SMS (Sanofi Manufacturing System) mindset within External Manufacturing and Supply operations. This role works transversally with Global Business Units (GBUs) to standardize, simplify, and optimize external manufacturing operations with Contract Manufacturing Organizations (CMOs), leveraging lean and SMS 2.0 principles and tools. The position ensures sustainability of the performance roadmap through a comprehensive upskilling program.

We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve lives.

Main Responsibilities

Performance Roadmap Deployment: 

• Coordinate, prepare, animate performance workshops focused on cycle time reduction, yield improvement, complex problem solving, and launch readiness. Lead and coordinate execution of related action plan

Performance Partnership: 

• Act as performance partner for one or more EM&S business units by attending leadership team meetings and performance rituals, supporting early detection of performance gaps and improvement opportunities, and driving prioritization and execution of initiatives

Performance Management System: 

• Deploy and maintain the EM&S performance management system according to SMS 2.0 standards, including +QDCI, Team Board, and GPS3 board

Operational Excellence Upskilling Program:

• Contribute to SMS upskilling program including training, certification, and coaching activities

• Cultural Change Leadership: Champion cultural change in continuous improvement, change management, and problem-solving methodologies

About You

Basic Qualifications

• Bachelors' degree required.

• 7+ years of relevant professional experience.

• Deep knowledge of performance management systems, continuous improvement methodologies, and problem-solving techniques. Proven track record of realizations.

• Expertise in sterile manufacturing and aseptic filling operations

• Expertise in biotech Drug Substance (DS) manufacturing

• Performance-oriented mindset with ability to understand and identify key performance drivers

• Cross-functional agility with demonstrated ability to operate effectively in matrix environments

• Strong communication skills with ability to establish and deliver impactful communications to senior leadership

• Coaching and training capabilities with experience developing others through structured support and feedback

• Change management and stakeholder engagement capabilities

• Fluent in English (written and verbal)

• Experience working with external partners and Contract Manufacturing Organizations (CMOs) is a plus

• SMS certification Intermediate or above (or equivalent Lean/Six Sigma)

• Experience in training, coaching, and people development is a plus

Why choose us?

•  Bring the miracles of science to life alongside a supportive, future-focused team. 

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. 

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. 

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

• Shape the future of medicine and vaccine delivery with cutting-edge technology, ensuring seamless launches and a resilient global supply.

• Power industry-leading performance by leveraging digital, data, and AI-driven innovation – at speed and scale

• Transform lives worldwide by delivering life-changing treatments anywhere, anytime.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SG

#LI-GZ

#vhd

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com