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Head of Finance - Rare Disease and Medical

Cambridge, Massachusetts Regular Posted on   Mar. 25, 2026 Closing on   May. 31, 2026 Salary Range   USD 161,250.00 - 232,916.66
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Job title: Head of Finance - Rare Disease and Medical

Location: Cambridge, MA

About the job

Ready to push the limits of what’s possible? Join Sanofi in one of our corporate functions and you can play a vital part in the performance of our entire business while helping to make an impact on millions around the world.  

Ready to push the limits of what's possible? Join Sanofi as a Finance Business Partner and become a catalyst for innovation in our Rare Disease portfolio and country Medical Functions. This strategic role directly impacts our ability to bring life-changing treatments to patients with rare conditions worldwide through successful launches of breakthrough therapies, orphan drugs and specialized treatments that address the unique challenges of smaller patient populations.

As the financial architect behind our Rare Disease and Medical capabilities growth strategy, you'll navigate complex financial landscapes including high-cost therapies, patient identification challenges, and specialty access dynamics while ensuring operational excellence across new product launches and lifecycle management initiatives. Your financial insights will shape critical business decisions, optimize investment strategies, and drive sustainable growth in alignment with Sanofi's mission to chase the miracles of science to improve people's lives.

This highly collaborative position offers countless opportunities to explore, make connections, and stretch the limits of what you thought possible while working with cross-functional teams across the Sanofi ecosystem.

At Sanofi, we are innovators committed to one purpose: chasing the miracles of science to improve people's lives. We embrace diversity in all its forms, fostering an inclusive environment where every employee can thrive and contribute to our mission. We're proud to be an equal opportunity employer committed to providing a workplace free from discrimination and harassment based on race, color, religion, gender, sexual orientation, gender identity, age, national origin, disability, veteran status, or any other protected characteristic.

Join us in transforming the practice of medicine and making a meaningful difference in patients' lives worldwide.

About Sanofi 

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. 

Main Responsibilities:

Strategic & Financial Leadership

  • Lead financial strategy and business partnering for existing in-line Brands and upcoming Rare Disease new launches, and integration activities

  • Lead financial strategy for North Americal Specialty Care Medical functions and business partnering with SPC Therapeutic Area Medical VPs and NAM SPC Head of Medical

  • Serve as primary finance partner guiding strategic decisions to achieve Net Revenue and BOI objectives

  • Provide thought leadership and financial oversight, applying critical thinking to optimize value and manage risks

  • Align financial and business strategies by partnering with stakeholders to evaluate investment trade-offs

Business Operations & Forecasting

  • Own full P&L responsibility including revenue planning, headcount, and operating expense controlling

  • Lead annual Budget, Forecast, and Strategic Plan processes with timelines and data validation

  • Oversee daily financial operations including inventory management, cash flow, and pricing dynamics

  • Anticipate and assess financial impact of business decisions across the full P&L

Performance Management & Reporting

  • Direct month-end close processes including sales analysis, GTN deductions, expense assessment, journal entries, balance sheet review

  • Deliver timely financial reporting, variance analysis, and business performance commentary

  • Drive monthly sales trend analysis with Commercial, Forecasting, and Data Analytics teams

  • Conduct in-depth Gross-to-Net analysis including balance sheet provisions and risk assessment

  • Define, monitor, and report key KPIs and launch readiness metrics

Integration & Launch Excellence

  • Partner with cross-functional teams to integrate financial processes for newly acquired business

  • Support business cases, scenario planning, and launch readiness assessments

  • Ensure cross-functional alignment and proactive risk mitigation for new launches

  • Supervise and lead Opex and Revenue Controllers overseeing commercial sales and operating expense budgets

AI & Digital Finance Enablement

  • Collaborate with AI and Commercial Analytics teams to enhance forecast models

  • Integrate AI capabilities to monitor sales trends and improve forecasting accuracy

  • Support finance system enhancements and digital transformation initiatives

Cross-Functional Collaboration & Governance

  • Present financial analyses to Senior Leadership including US & Global teams, Head of NA SPC, and Executive Leadership

  • Support internal controls and external audit requirements

  • Promote finance best practices in partnership with One-Finance

  • Actively collaborate with Sales & Marketing, Market Access, Patient Services, Supply Chain, and Business Operations

Key Business Partners

  • US Rare Disease General Manager

  • NAM SPC Head of Medical and TA Medical VPs

  • Sales Leadership, Marketing, and Patient Support Services

  • Market Access and Business Operations (Forecasting & Analytics)

  • Global Supply Chain

  • Global Finance and One-Finance

About You

Qualifications:

  • Bachelor's degree in Finance, Accounting, or related field required

  • 5+ years of progressive finance experience

  • CPA or MBA preferred

  • Pharmaceutical industry controlling experience preferred

  • Strong understanding of financial concepts including Revenue and Expense controlling

  • Proven experience in Gross-to-Net forecasting and analysis

  • Proficiency with SAP and TM1

  • Advanced Excel skills (pivot tables, VLOOKUPs, macros, data analysis)Demonstrated business partnering ability in complex matrix organizations

Key Competencies & Attributes:

  • Strategic thinker with strong analytical and problem-solving skills

  • Exceptional leadership qualities with ability to influence senior stakeholders

  • Strong business acumen and commercial orientation

  • Effective communicator with executive presence

  • Results-driven with focus on operational excellence

  • Ability to adapt priorities in a fast-paced environment

  • Ability to synthesize macroeconomic, industry, and internal data to shape strategy

Why Choose Us?  

  • Bring the miracles of science to life alongside a supportive, future-focused team. 

  • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. 

  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. 

  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. 

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. 

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

Pursue Progress. Discover Extraordinary.

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Final compensation will be determined based on factors such as experience, skills, expertise, location, and others. Employees may be eligible to participate in company employee benefit programs.

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