Global Rare Diseases Therapeutic Area Head, LSDs and Cablivi
Cambridge, Massachusetts Regular Posted on Aug. 10, 2026 Closing on Oct. 10, 2026 Salary Range USD 293,250.00 - 423,583.33Job Title: Global Rare Diseases Therapeutic Area Head, LSDs and Cablivi
Location: Cambridge, MA
About the Job
Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs.
Reporting to the Global Head of Rare Diseases and as a member of the Global Rare Diseases Franchise Leadership Team (GRDLT), Global Rare Diseases TA Head, LSDs and Cablivi has the responsibility to manage Sanofi’s LSD portfolio and Cablivi globally in coordination with markets and global functions.
Key Assets: Fabrazyme, Cerezyme, Cerdelga, venglustat (GD3 and Fabry), Xenpozyme , Myozyme, Nexviazyme, Aldurazyme and Cablivi.
We are an innovative global healthcare company, committed to transforming the lives of people with immune challenges, rare diseases and blood disorders, cancers, and neurological disorders. From R&D to sales, our talented teams work together, revolutionizing treatment, continually improving products, understanding unmet needs, and connecting communities. We chase the miracles of science every single day, pursuing Progress to make a real impact on millions of patients around the world.
About Sanofi
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Main Responsibilities:
Drive Global P&L accountability and lead strategic and financial planning for brands, developing sales and expense forecasts to maximize portfolio value
Define and drive brand strategies for the LSds+ Cablivi portfolio, positioning Sanofi as the leader in LSDs and TTP / Rare disease space across key markets globally
Lead the global launch of venglustat in GD3 and Fabry working global functions and in-country teams ensuring execution that maximizes the global strategy to defend and grow our Gaucher and Fabry businesses. Execute the co-positioning narrative for Gaucher and Fabry to maximize value for Sanofi
Continue to transform and modernize our LSD business by ensuring global OPEX in-line with brand spending guidelines, go-to-market models are optimized, and content generation is 100% AI-generated
Lead all supply and demand discussions with M&S and cross functionally ensuring continuity of care for all patients and avoiding stockout risk
Manage all supply constraints working with the M&S team and countries to avoid out-of-stock situations and, more importantly, patient impact
Direct all portfolio-level, cross-LSD market shaping, Find , Treat and Maintain LSDs by creating new roles with new perspectives on the team
Continue to grow Cablivi in aTTP focusing on patient find initiatives in the key countries
Prepare IR for earnings calls by providing clear business updates along with the LSD narrative that captures the opportunities and challenges surrounding the portfolio
Build and develop a best-in-class team with a winning culture, and foster strong cross-functional collaboration across the organization
Act as a member of the Global Rare Diseases Leadership Team and demonstrate enterprise leadership by sharing best practices, mentoring talent, contributing to franchise-level initiatives and events
About You
Experience & Qualifications:
A minimum of a Bachelor’s Degree is required. MBA, MS or PhD in life science is preferred
Extensive and diverse industry experience: A minimum of 15 years of experience in the pharmaceutical industry, across various functions (e.g., sales, marketing, MA, BD, NPP, etc.), including in US/key markets
Leadership and brand management: experience in leading teams and brand/portfolio strategies in US/key markets is required
Current or prior experience managing global brands is preferred
Launch and pre-launch experience: strong track record in successfully launching and pre-launching products in US/key markets is required
Strong credibility in P&L management
Cross-functional enterprise leadership and strong capacity to drive decision-making with key internal stakeholders is require
Stakeholder engagement: ability to advocate for Sanofi’s vision, and negotiate and drive value from key partnerships, such as alliances, analysts and the investment community, patient organizations, and scientific institutions is required)
Demonstrated ability to work collaboratively in a matrixed environment with many cross-functional partners including marketing brand teams, market research, market access, medical affairs, business development, regulatory, research & development, manufacturing, finance and legal
Ability to work in a fast-paced environment and quickly adjust to changing priorities is essential
Excellent interpersonal, oral and written communication skills, including ability to synthesize and deliver a clear overview of the strategy, opportunity and risks for Sanofi executives
This position may require up to 25% overall travel
Valid passport and ability to travel internationally
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
Pursue Progress. Discover Extraordinary.
Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.
Final compensation will be determined based on demonstrated experience, skills, location, and other relevant factors. Employees may be eligible to participate in Company employee benefit programs.
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