Job Title: Senior Technician

• Location : Vitry-sur-Seine – France
• Type de contract : CDI de Chantier de 18 mois

About the job

As Senior Technician within the WIDGeT consortium (Viral Vector Intelligent Design for Gene Therapy), you will execute and design complex molecular biology experiments focused on single-cell applications using NGS technology. You will work on developing innovative technology to provide sensitive information of AAV transgene expression at the single-cell level, leveraging droplet microfluidics, DNA barcoding, and scRT-PCR. Your expertise will directly contribute to accelerating the development of gene therapies for age-related macular degeneration and hereditary kidney diseases. Ready to get started?

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world.

Key Responsibilities:

• Execute and design complex molecular biology experiments with focus on single-cell applications, NGS analysis, and protocol optimization
• Analyze experimental data and write laboratory documentation, presenting research findings in clear and professional formats
• Co-supervise technicians and undergraduate students involved in the research project
• Report progress and collaborate with other members of the WIDGeT consortium
• Maintain and optimize laboratory workflows using advanced technologies including droplet microfluidics, FACS, PCR, qPCR, and NextSeq Illumina sequencing
• Contribute to the development and validation of innovative single-cell analysis methodologies

About you

Experience:

• Experience in molecular biology with hands-on expertise in PCR, purification, and NGS experiments and analysis.
• Background in single-cell assays (flow cytometry).
• Experience with low-input molecular biology assays (single-cell RNA sequencing, 10X, PARSE). Experience with protocol optimization and routine laboratory techniques.
• Familiarity with recombinant AAV, organoids/tissues preparation, or screening is a plus

Technical and Soft Skills:

• Hands-on experience with routine laboratory techniques and experimental workflow.
• Familiarity with statistical software (Prism, Spotfire, or equivalent).
• Interest in bioinformatics and ability to work on challenging projects.
• Ability to co-supervise and mentor junior team members

Education: BUT/DUT or Master's degree in Biology or Molecular Biology

Languages: Proficiency in both French and English (written and spoken).

Why choose us?

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions

• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Enjoy opportunities to collaborate beyond your area of expertise, working with diverse teams across science, clinical, and digital fields to spark new ideas and drive breakthroughs.
• Accelerate your professional development with structured career paths designed for both scientific and leadership advancement. Grow in ways you never imagined through bold moves that stretch your potential, cross moves into other business areas, and short-term gigs that build your scientific expertise.

Pursue Progress. Discover Extraordinary

Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Let’s Pursue Progress and Discover Extraordinary – together.

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.

Le contenu du poste est libellé en anglais car il nécessite de nombreuses interactions avec nos filiales à l'international, l'anglais étant la langue de travail.