
Activités Industrielles
Là où les miracles
de la science
deviennent une réalité pour les patients
Head of Sanofi Manufacturing System (SMS) Program
En bref
Nos équipes produisent et livrent chaque année plus de 4 milliards de médicaments et de vaccins, veillant à ce que chaque avancée soit accessible à ceux qui en ont le plus besoin. Grâce à des infrastructures ultra-modernes, des usines intelligentes pilotées par l’IA et une automatisation de pointe, nous repoussons les limites pour garantir que nos traitements parviennent aux patients plus rapidement, en toute sécurité et de manière plus durable que jamais. C’est ici que votre expertise, votre ambition et votre passion peuvent façonner l’avenir de la santé.
Job Title: Head of Sanofi Manufacturing System -SMS Program
Location: Swiftwater, PA
About the Job
We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.
The Head of Sanofi Manufacturing System (SMS) Program provides strategic leadership and oversight for the SMS operational excellence program at the Swiftwater site. This role is responsible for directing and coordinating all SMS activities, including strategic programs, SMS 2.0 implementation, upskilling efforts, and performance improvement initiatives. The position leads a team of SMS Program Leads and Performance Champions who execute specialized functions within the SMS framework, ensuring alignment between site-level execution and global strategic objectives. As a primary SMS champion for the site, this role drives operational excellence initiatives that enhance manufacturing performance, reduce costs, and develop organizational capabilities while ensuring the successful delivery of Compelling Business Needs (CBNs) and Foundational Elements (FEs).
We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?
Main Responsibilities:
Driving performance & transformation initiatives for deployment
Working for the Head of Operational Excellence, this role establishes the strategic vision and roadmap for SMS implementation across the Swiftwater site
Oversee the planning, governance, and measurement of the U.S. Vaccines strategy and portfolio of strategic initiatives
Align site SMS initiatives with global function strategies and business objectives
Champion the integration of SMS standard methodologies across all operational areas utilizing effective change management practices
Prioritize initiatives with partner departments based on strategic importance and resource availability
Oversees the delivery of extensive in-person and remote SMS training programs
Ensuring Impact & Sustainability
Foster a culture of continuous improvement and operational excellence
Align SMS program investments with expected business outcomes
Oversee the site's Cost of Goods Manufactured (COGM) reduction efforts and resultant savings trajectory
Review and approve business cases for high-value strategic initiatives
Establish key performance indicators (KPIs) for measuring SMS program effectiveness, monitor progress, and address performance gaps
Ensure effective execution of Transform the Business (TTB) meetings with the Site Leadership Team
Manage site employees' progression within the SMS Certification maturity program
Contributing to the development of Operating Standards in close partnership with dedicated leaders and supporting M&S network
Develop and maintain comprehensive governance structures across the site to ensure consistent SMS execution
Partner with site leadership team to integrate SMS principles into all operational areas
Represent the site's SMS program in global/GBU/site leadership forums
Collaborate with global SMS teams and other sites to ensure alignment between site standards and global SMS frameworks
Coordinate SMS 2.0 maturity assessments and process confirmations with site’s SMS Area Heads
Develop and lead the site's program for upskilling and coaching of SMS methodology, standards, and tools
Lead the development and refinement of SMS operating standards for the site in coordination with global teams
About You
Required Qualifications
Education: Bachelor's degree in Engineering, Life Science, Business, Operations Management, or related field. SMS Intermediate certification or equivalent lean and/or six sigma certification from reputable organization (AME, ASQ, LEI, LSSI, etc).
Work Experience: 10+ years of experience in manufacturing operations or operational excellence roles with at least 5 years in leadership positions. Demonstrated success implementing manufacturing systems or operational excellence programs at scale.
Transformation and Change Management Skills: Expert knowledge of SMS/TPS/similar operating standards and operational excellence methodologies. Proven experience leading large-scale transformation initiatives and managing complex change.
Technical Knowledge: Understanding of pharmaceutical manufacturing processes and regulatory requirements. Strong grasp of financial concepts including P&L, BOI, COGM, cash flow, and performance management systems. Solid understanding of data management & digital products embedded into the SMS operating standards.
Analytical Skills: Advanced analytical capabilities for strategic decision-making and performance analysis. Experience with data-driven improvement methodologies and digital transformation initiatives.
Project Management: Extensive experience managing complex, cross-functional programs and project portfolios. Ability to develop and execute strategic roadmaps across multiple workstreams.
Leadership & Coaching: Exceptional leadership skills with demonstrated ability to influence at all organizational levels. Experience building and developing high-performing teams and coaching leaders.
Communication: Superior communication and presentation skills for engaging with executive leadership. Ability to articulate complex concepts clearly and persuasively to diverse audiences.
Preferred Qualifications:
Education: Master's degree in Engineering, Life Science, Business, Operations Management, or related field. SMS Advanced Certification or equivalent lean and/or six sigma certification from reputable organization (AME, ASQ, LEI, LSSI, etc).
Work Experience: 15+ years of experience in manufacturing operations or operational excellence roles with at least 8 years in senior leadership positions. Experience leading operational excellence programs across multiple sites or global functions.
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

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Pourquoi nous rejoindre ?
- Nous ne faisons pas que fabriquer des médicaments—nous créons un impact. Grâce à notre réseau international d’installations de pointe, nous veillons à ce que les patients reçoivent les traitements dont ils ont besoin, au moment où ils en ont besoin.
- L’innovation est notre moteur. De la fabrication pilotée par l’IA aux méthodes de production inédites, nous repoussons les limites de l’efficacité et de la performance.
- Ici, vous évoluez. Que ce soit en production, en qualité, en ingénierie ou en supply chain, vous collaborerez avec des experts de renom, développerez vos compétences et contribuerez à façonner l’avenir de l’industrie pharmaceutique.
- Nous faisons ce qui est juste. Sécurité, durabilité, diversité, équité et inclusion sont au cœur de notre engagement, garantissant un environnement où chacun peut s’épanouir.
Tous engagés pour la diversité
Chez Sanofi, la diversité des perspectives est une source d’innovation au service des patients. Découvrez Hamza Laajaj, Chef de projet déploiement applicatif à Neuville-sur-Saône, et son engagement pour un environnement inclusif où chaque voix compte. Pour lui, c’est en embrassant la diversité que nous libérons l’innovation et repoussons les limites de la santé.

"Nous faisons ce qui est juste. Sécurité, développement durable, diversité, équité et inclusion sont au cœur de notre engagement, garantissant un environnement où chacun peut s’épanouir."

Brendan O’Callaghan
Executive Vice President of Manufacturing and Supply
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