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Senior Associate Scientist, Protein Production and Characterization

Cambridge, Massachusetts Permanent Posté le   Jul. 01, 2025 Expire le   Jul. 07, 2025 Salary Range   USD 73,500.00 - 106,166.66
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Job Title: Senior Associate Scientist, Protein Production and Characterization

Location: Cambridge, MA

About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate Progress. 

The Large Molecule Research (LMR) group is a platform organization that supports early-stage protein therapeutic research at Sanofi. Our global team interfaces with the therapeutic areas and CMC development to deliver first-in-class and best-in-class medicines to treat diverse disease areas.

We are seeking a highly motivated candidate to join the Biologics Characterization, Expression, and Purification (BiCEP) team as a Senior Associate Scientist. The lab-based candidate will be responsible for production and analysis of protein tools and therapeutic candidates. They will work closely with other LMR functional groups (Antibody Discovery, Molecular Biology & Screening Technology, Protein Engineering) as well as cross-functional project teams to discover new therapeutic antibodies. Success in this position requires strong expertise in protein characterization, ability to propose innovative solutions to workflow challenges, and ability to communicate scientific results to mixed (expert/non-expert) audiences. The position is located in Cambridge, Massachusetts.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main Responsibilities:

  • Express and purify recombinant antibodies, antigens, and fusion proteins from mammalian expression systems

  • Perform analytics to ensure the purity, quality, and function of recombinant proteins

  • Initiate, design, and perform innovative technology development experiments

  • Present data to department and project teams

  • Ensure thorough and compliant experimental data capture to enable training of ML/AI algorithms

  • Interface with digital teams to automate data management bottlenecks

About You

Qualifications:

  • Bachelor’s or master’s degree in Biochemistry, Biotechnology, Biology, Biomedical Engineering or a related field

  • 5+ years of industry experience (bachelor’s degree) or 2+ years of industry experience (master’s degree)

  • Demonstrated ability to independently design and execute experiments

  • Hands-on experience with transient and stable mammalian protein expression

  • Experience with protein purification using automated (AKTA) systems

  • Background in bioconjugation to produce & characterize non-standard protein formats

  • Expertise in protein analytical techniques, such as HPLC, mass spectrometry, SPR (Biacore/Carterra), BLI (Octet), SDS-PAGE, ELISA, Western blotting

  • Ability to present findings to diverse scientific groups in clear and concise manner

  • Strong analytical and problem-solving skills

Why Choose Us?

  • Bring the miracles of science to life alongside a supportive, future-focused team.

  • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.

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