Vaccines
Where
extraordinary minds
help protect half a billion people
mRNA CoE Operational Excellence Leader - Vaccines
Who we are
Every day, 2.5 million Sanofi vaccine doses reach patients worldwide - powered by bold ideas, cutting-edge science, and passionate people like you. Across every stage — from discovery to delivery — Sanofians are shaping the future of vaccines. In global R&D hubs, exceptional offices, and state-of-the-art manufacturing sites, we’re reimagining what’s possible. But science alone isn’t enough — it’s the extraordinary minds behind it that truly make the difference.
Job title: mRNA CoE Operational Excellence Leader - Vaccines
Location: Waltham, MA
About the job
As Function OE Leader within our Vaccine mRNA team you’ll take ownership on improvement & performance initiatives. Ready to get started?
About the job:
Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization.
The Function OE Leader is responsible for supporting the deployment of the
VRD Excellence Model (VRD EM) within their assigned function, in alignment
with the global OE strategy. This role empowers operational teams to take
ownership on improvement & performance initiatives by providing coaching,
training, and methodological support. The Function OE Leader fosters an
impact - driven and improvement - oriented culture by enabling teams to apply
OE principles, tools, and routines effectively to achieve function ambitions.
About Sanofi:
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Main Responsibilities:
1) Operational Excellence Deployment within the function
Conduct diagnostics and/or gap analyses (business case) with operational teams to identifyimprovement opportunities.
Propose the most appropriate methodology for each improvement initiative within the function .
Ensure that each improvement initiative within the function complies with the core principles ofOperational Excellence.
Support or l ead improvement initiatives within the function when specific OE competencies arerequired
Proactively support function performance and measure the impact of the initiative
Guarantee the practical problem - solving (standard improvement) process and ensureconsistency in the implementation of improvement ideas.
Monitor and report Progress of OE activities (improvement initiatives, level 2 practical problem-solving, and improvement ideas) to the Head of Function OE.
Ensure sustainability of improvements by integrating them into function performancemanagement routines.
Identify impacts, define change strategy, check the gaps for efficient adoption , etc
2) Capability Building within the function
Identify individual OE development needs required to implement the function improvementinitiatives. Build the training plan in alignment with the function’s Operational Excellence roadmap improvement priorities.
Deliver OE training and coaching to improvement initiative leaders and members based on thedefined training plan
Conduct skill assessment and validation for initiative leaders.
Promote feedback culture and continuous learning mindset.
Ensure adoption and application of OE standards, routines, and methodologies.
3) Cross - functional Collaboration
Participate in transversal and cross - functional initiatives impacting the function.
Share best practices and contribute to harmonization of OE efforts across functions.
Contribute to the OE community by promoting the replication of effective approaches.
4) Knowledge Management
Perform return - on - experience process and support capitalization efforts from past initiatives.
Identify, document, and share lessons learned and successful practices.
Expected key impacts:
Improved Function performance through better use of OE levers by operational teams.
Enhanced OE capabilities by developing operational teams’ skills in OE methodologies, tools and standards core principles,
Stronger adoption of OE culture driven by active involvement of operational teams in improvementefforts.
Sustainable change enabled by teams becoming autonomous in applying OE principles.
Job Complexity (main elements defining the complexity of the job):
Matrix Collaboration: Operate as change agent and business partner influence without direct authoritywithin a matrix organization,
Cultural & Behavioral Change: continuous improvement is still maturing.
Drives mindset shifts and OE adoption in environments where
Stakeholder Management: Engages a wide range of stakeholders—from shopfloor to leadership—each with differing expectations, levels of engagement, and resistance to change.
Sustainability of Impact: Ensures OE initiatives are not one- offs but integrated into business routines, with long - term adoption and measurable performance impact.
About You:
Education/Experience:
Bachelor’s or master’s degree (e.g., Engineering, Life Sciences, Business or relevant field), with at least 5 years of experience in Operational Excellence
Basic Qualifications:
Operational excellence, agile and Lean methodologies experiences.
Experience working in a matrix and cross-functional environment.
Workshop animation: Skill in leading interactive and structured workshops to co-build solutions with teams.
Project management: Ability to plan and execute projects , including risk mitigation, timeline tracking, and stakeholder alignment. (finance management, resource management, business case…).
Problem solving: Strong root cause analysis and structured problem-resolution capabilities.
Desirable Qualifications:
Change management: Familiar with change models and techniques to foster adoption and engagement.
Training & coaching: Competency in educational training design, storytelling, and facilitation techniques to transfer knowledge and inspire teams.
Data analysis: Proficient in analyzing performance data to inform decisions and monitor impact.
Ability to bridge digital innovation with operational excellence.
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
Pursue Progress. Discover Extraordinary.
Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what’s never-been-done-before. You’ll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people’s lives? Let’s Pursue Progress and Discover Extraordinary – together.
At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.
Watch 'One day at Sanofi' and check out our Diversity Equity and Inclusion initiatives at sanofi.com
Final compensation will be determined based on demonstrated experience, skills, location, and other relevant factors. Employees may be eligible to participate in Company employee benefit programs.
Find out more about this location
Why work with us
- We’re problem-solvers and pioneers. United by the belief that everyone deserves a healthier future. We create best-in-class vaccines that prevent disease and protect lives.
- Innovation drives us. From AI and mRNA to next-gen science, we push the boundaries to deliver first- and best-in-class vaccines for infectious diseases worldwide.
- Growth happens here. With bold investments in R&D and world-class facilities, Sanofians across the entire vaccine lifecycle are shaping the future of global health.
- We do what’s right. Sustainability and DE&I drive our positive global impact—because the diverse communities Sanofians represent are the patients we serve.
What does it take to protect the world from disease?
For over a century, we’ve been pioneering breakthroughs that help protect millions from diseases like polio, influenza, RSV, and more. And we’re not stopping there.
Powered by groundbreaking technologies - mRNA platforms, recombinant proteins, and AI-driven insights - we’re pushing the boundaries of science.
"I’m immensely proud of the pace of our innovation – the urgency by which our teams are working to transform the practice of medicine."
Thomas Triomphe
Executive Vice President, Vaccines
Discover more
Sanofi’s mRNA Center of Excellence
Step into the future of healthcare with Sanofi’s mRNA Center of Excellence. Discover how a global team is transforming medicine with cutting-edge mRNA technology – and explore the skills, inspirations, and breakthroughs driving this revolution. Ready to shape the future?
About Sanofi Vaccines
Explore our commitment to protecting global health through the power of vaccines. We’re building healthier communities with innovative solutions that save millions of lives each year. Dive into the future of vaccines, discover the diseases we’re tackling, and learn why vaccination is critical at every stage of life.
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